Abstract
Inhibition of SARS-CoV-2 Variants In the article number 2206154, Ievgen S. Donskyi and co-workers describe effective SARS-CoV-2 inhibitor. Low molecular weight polyglycerol sulfate works in tandem with a single hydrophobic fullerene to prevent the infection in vitro. Investigated through plaque reduction assays, microscale thermophoresis (MST) binding studies, and molecular dynamics (MD) simulations, fullerene appears to nestle in to a solvent accessible hydrophobic pocket on the S1 spike protein.
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