Abstract

Several important challenges remain to be met in the successful engineering of cartilage tissue constructs. In this study we address the need to engineer anatomically‐shaped constructs of entire articular layers for the treatment of joints with widespread degenerative disease. Reconstructing the anatomic contours can be achieved with a variety of techniques, including non‐invasive imaging such as MRI and CT. Calibrating the accuracy of such techniques can be performed on cadaver specimens using techniques such as stereophotogrammetry and laser scanning. A review of these methods will be provided in this presentation, along with recent advances in the engineering of mechanically functional cartilage tissue constructs.

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