Abstract
Chronic experiments were staged on 3 adult dogs. For a period of 3–6 months a study was made of the functional state of the respiratory center and dynamics of respiratory arrhythmia during increase of the vagus center tone induced by subcutaneous administration of low morphine doses and subsequent intravenous injection of calcium chloride. When the heart rate is slow there is a reduction of the frequency of respiratory motions; the least respiration rate corresponded to the least pulse rate. The coefficient of respiratory arrhythmia increased against the background of relatively slow respiration with a gradual slowing of cardiac contractions. Against the background of frequent respiration, sinus arrhythmia was not connected with respiration, notwithstanding the considerable reduction in pulse rate.
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