Abstract
The therapy of burns is a challenging clinical issue. Burns are long-term injuries, and numerous patients suffer from chronic pain. Burn treatment includes management, infection control, wound debridement and escharotomy, dressing coverage, skin transplantation, and the use of skin substitutes. The future of advanced care of burn wounds lies in the development of “active dressings”. Hydrogel dressings have been employed universally to accelerate wound healing based on their unique properties to overcome the limitations of existing treatment methods. This review briefly introduces the advantages of hydrogel dressings and discusses the development of new hydrogel dressings for wound healing along with skin regeneration. Further, the treatment strategies for burns, ranging from external to clinical, are reviewed, and the functional classifications of hydrogel dressings along with their clinical value for burns are discussed.
Highlights
Between 2015 and 2019, 550,000 people worldwide died from fire, heat and hot substances, and 37 million people were disabled and requiring medical treatment (World Health Organization., 2019)
The debridement and excision of contaminated necrotic tissue and eschar improve the visibility of the wound surface (Latenser, 2009; Sen et al, 2009), prevent fragile eschar from being stretched and causing pain in damaged skin areas, and improve the limb ischemia caused by large-area eschar contraction (Dries, 2005)
Targeting many problems faced in the repair process of burn wounds, the functionalities of dressings can be designed during the construction of hydrogel dressings
Summary
Between 2015 and 2019, 550,000 people worldwide died from fire, heat and hot substances, and 37 million people were disabled and requiring medical treatment (World Health Organization., 2019). >95% of these burn injuries occur in low- and middle-income countries (Peck, 2011). Severe burns continue to pose a major challenge in regions with limited medical resources, especially developing countries. With the continuous improvement of burn care, development of new burn dressings is crucial
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