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Functional Activity of Hip Muscles in Patients With Severe Dysplastic Coxarthrosis

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Background Despite recent advances in surgical treatment of dysplastic coxarthrosis, muscular dysfunction of the affected extremity and attempts to improve its functional capacity represent a significant problem. Materials and Methods A prospective case‐match study of 50 patients with severe dysplastic coxarthrosis was conducted. Initially, at 3 and 6 months, all patients were evaluated with handheld dynamometry (HHD), surface electromyography (sEMG), and Harris scoring. The study arm consisted of 25 patients with severe dysplastic coxarthrosis Crowe III‐IV who underwent total hip arthroplasty. The control arm consisted of 25 consecutive patients who underwent conservative treatment due to the refusal of total hip arthroplasty. Results A progressive increase in muscle strength, amplitude, and electrical activity was observed in the study arm. Statistically significant differences were observed for the Harris index in patients in the study arm at 3 and 6 months –65.00 ± 3.69 and 47.00 ± 5.85 points at 3 months and 85.31 ± 1.40 and 44.00 ± 4, 92 points at 6 months, respectively. Total hip arthroplasty was found to be a significant prognostic factor for functional recovery of the muscles of the lower extremities ( p = 0.034, RR – 2.287, CI: 0.023 – 9.301). Conclusions The results of our study suggest that total hip arthroplasty in patients with severe dysplastic coxarthrosis was associated with increased muscular strength, amplitude of the bioelectrical potential, and physical activity of the hip muscles. These findings could have a significant beneficial impact on the improvement of functional recovery in this category of patients.

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  • Research Article
  • 10.37647/0132-2486-2021-109-2-25-33
Peculiarities of Preoperative Planning of Total Hip Arthroplasty in Patients with Hip-Lumbar Syndrome
  • Oct 12, 2021
  • Visnyk Ortopedii Travmatologii Protezuvannia
  • O.M Sulyma + 6 more

Summary. At present, no scheme of approach to surgical treatment of patients with hip-lumbar syndrome (HLS) depending on the type of vertical posture and the type of bone formation and progression of coxarthrosis is developed. The decision of these questions, interesting from the scientific and practical point of view, is an actual task of modern orthopedics and defines features of preoperative planning of total hip arthroplasty (THA) in patients with HLS.
 Objective: to determine the features of preoperative planning of total hip arthroplasty in patients with hip-lumbar syndrome.
 Materials and Methods. The basis for the development of recommendations for preoperative planning of THA in patients with HLS was the data of retrospective analysis of medical histories of 138 patients who underwent hip arthroplasty in the Department of Orthopedics and Traumatology of Adults of SI “Institute of Traumatology and Orthopedics of NAMS of Ukraine”. The data of the clinical study of 506 patients with idiopathic, dysplastic and post-traumatic coxarthrosis conducted earlier were also taken into account, and the tactics of treatment in cementless hip arthroplasty was developed.
 Results. It was determined that the vertical posture affects the progression of coxarthrosis and the nature of the lesion of the lumbar spine in patients with HLS. Patients with a certain hypolordotic posture and a rapid course of coxarthrosis are recommended to undergo primary decompression of the spinal roots and THA at the second stage. In other cases, the initial implementation of THA is recommended. Recommendations for the use of the type and method of fixation and coverage of the leg of the endoprosthesis depending on the type of bone formation in the HLS of the examined patients are developed.
 Conclusions. Taking into account the features of preoperative planning of THA in patients with HLS will reduce the number of negative results and complications of this category of orthopedic patients.

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  • Cite Count Icon 16
  • 10.2174/1874325001307010158
Eleven Year Results of Total Hip Arthroplasty in Patients with Secondary Osteoarthritis Due to Slipped Capital Femoral Epiphysis
  • May 17, 2013
  • The Open Orthopaedics Journal
  • Benjamin Schoof + 6 more

Background:Total hip arthroplasty (THA) in patients with a history of Slipped Capital Femoral Epiphysis (SCFE), is typically indicated to address the consequent deformity of the proximal femur and/or acetabulum. It can be a challenging procedure for the orthopaedic surgeon. Previous studies have focused on prevention of osteoarthritis post-SCFE. However, there is a paucity of data on the outcomes of total hip arthroplasty in patients with osteoarthritis secondary to SCFE. This study was performed to assess the mid-term results of total hip arthroplasty in this patient cohort.Materials and Methods:All patients with secondary osteoarthritis due to slipped capital femoral epiphysis, treated with total hip arthroplasty between 1987 and 2005, were included in this retrospective study (n=30). Thirty patients (17 male, 13 female) met the inclusion criteria with one patient lost to follow-up and one unrelated death one year before follow up examination, thereby leaving 28 patients (32 hips) eligible for the study with a mean follow-up time period of 11.2 years. The Harris Hip Score (HHS) and MOS 36 short form health survey (SF36) were determined preoperatively and at most recent follow-up for all patients. Complications were also noted for all cases.Results:The mean Harris Hip Score increased significantly from 47 (32-59; SD=8.3) to 92.3 (65-100; SD=8.2) (p<0.0001). The SF-36 health survey showed an improvement of quality-of-life in all sub-scales. Overall, revision surgery was required in six cases (19 %). Aseptic loosening, leading to implant removal, was noted in five cases. A single-stage revision to address infection was performed in one case. The cumulative survival rate at latest follow-up was 81 %. No other complications were encountered during the study.Conclusions:Despite a higher failure rate, compared to total hip arthroplasty in the treatment of primary osteoarthritis, total hip arthroplasty can be considered a feasible option for patients with secondary osteoarthritis of the hip due to slipped capital femoral epiphysis. The current study demonstrates good outcomes in patients treated with a cementless column-preserving prosthesis, which is of particular relevance for this young patient cohort. However, further clinical prospective randomized studies are warranted to provide more definitive evidence.

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  • Cite Count Icon 9
  • 10.1007/s00402-018-2899-8
Incidence of perioperative complications in total hip and knee arthroplasty in patients with Parkinson disease.
  • Feb 15, 2018
  • Archives of orthopaedic and trauma surgery
  • Tankamani Sharma + 5 more

The aim of this study is to evaluate the difference in perioperative complication rate in total hip, bipolar hemiarthroplasties and total knee arthroplasty in patients with Parkinson disease in trauma and elective surgery in our Musculoskeletal Center during a period of 10 years. Between 2006 and 2016, 45 bipolar hemiarthroplasties in trauma surgery, 15 total knee and 19 total hip arthroplasties in patients with Parkinson's disease were performed. We divided the patients in two groups. Group I included trauma cases (45) and group II elective surgery cases (34). Complications were documented and divided into local minor and major complications and general minor and major complications. Fisher's exact test was used for statistical evaluation. In both groups, there was one local major complication (p > 0.05): In group I, there was one case of loosening of a K-wire which was removed operatively. In group II, there was one severe intraarticular bleeding requiring puncture of the hematoma. In group I, there were 38 general complications; in group II, there were 17 general complications. There was no statistical difference in complication rate (p > 0.05). Total hip arthroplasty, bipolar hemiarthroplasties and knee arthroplasty in patients with Parkinson disease is possible in elective and trauma surgery. Complication rate is higher in comparison with patients not suffering from Parkinson disease, but there is no difference in complication rate in elective and trauma surgery. Nevertheless, early perioperative neurological consultation in patients with Parkinson disease is recommended to minimize complications and improve early outcomes after arthroplasty.

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  • Cite Count Icon 3
  • 10.7507/1002-1892.202003053
Safety and effectiveness of total hip arthroplasty in patients with hypothyroidism
  • Oct 15, 2020
  • Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • Mingcheng Yuan + 4 more

To evaluate the safety and effectiveness of total hip arthroplasty (THA) in patients with hypothyroidism. Sixty-three patients with hypothyroidism (hypothyroidism group) and 63 euthyroid patients without history of thyroid disease (control group) who underwent primary unilateral THA between November 2009 and November 2018 were enrolled in this retrospective case control study. There was no significant difference between the two groups in gender, age, body mass index, hip side, reason for THA, American Society of Anesthesiology (ASA) classification, preoperative hemoglobin (Hb) level, and preoperative Harris score ( P>0.05). The perioperative thyroid stimulating hormone (TSH) and thyroxine (T 4) levels, the hypothyroidism-related and other complications during hospitalization, the decrease in Hb, perioperative total blood loss, blood transfusion rate, length of hospital stays, and 90 days readmissions rate in the two groups were recorded and evaluated. The periprosthetic joint infection, aseptic loosening of the prosthesis, and hip Harris score during follow-up were recorded. The differences in the TSH and T 4 of hypothyroidism group between pre- and 3 days post-operation were significant ( P>0.05) and no hypothyroidism-related complications occurred after THA. The decrease in Hb and perioperative total blood loss in the hypothyroidism group were significantly higher than those in the control group ( P<0.05), but there was no significant difference between the two groups in terms of transfusion rate, length of hospital stays, and 90 days readmission rates ( P>0.05). No significant difference in the rate of complications (liver dysfunction, heart failure, pulmonary infection, urinary infection, and wound complication) between the two groups was found ( P>0.05) except for the rate of intramuscular vein thrombosis which was significantly lower in the hypothyroidism group, and the rate of postoperative anemia which was significantly higher in the hypothyroidism group ( P<0.05). The two groups were followed up 1.0-9.9 years (mean, 6.5 years). At last follow-up, Harris score in both groups were significantly higher than those before operation ( P<0.05). An increase of 39.5±12.3 in hypothyroidism group and 41.3±9.3 in control group were recorded, but no significant difference was found between the two groups ( t=0.958, P=0.340). During the follow-up, 1 case of periprosthetic joint infection occurred in the hypothyroidism group, no loosening or revision was found in the control group. With the serum TSH controlled within 0.5-3.0 mU/L and T 4 at normal level preoperatively, as well as the application of multiple blood management, hypothyroid patients can safely go through THA perioperative period and effectively improve joint function, quality of life, and obtain good mid-term effectiveness.

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  • Cite Count Icon 1042
  • 10.1302/0301-620x.64b1.7068713
The direct lateral approach to the hip.
  • Feb 1, 1982
  • The Journal of Bone and Joint Surgery. British volume
  • K Hardinge

A direct lateral approach to the hip is described which allows adequate access for orientation of the implant, for the insertion ofthe cement and for the correction ofdiscrepancy in leg length. An anatomical observation was made that the gluteus medius muscle is inserted into the greater trochanter by a tendon and that the axis of the shaft of the femur lies anterior to the main bulk of the muscle which was left

  • Research Article
  • 10.7507/1002-1892.201707106
Safety and efficacy of total hip arthroplasty in patients with end stage renal disease
  • Dec 1, 2017
  • Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • Qiang Xiao + 8 more

To evaluate the safety and efficacy of total hip arthroplasty (THA) in patients with end stage renal disease (ESRD). Between December 2009 and May 2016, 30 THAs were performed in 28 patients with dialysis-dependent renal failure (18 patients) or renal transplantation (10 patients). A retrospective case control study was carried out to compare these 28 ESRD patients (ESRD group) with a matched cohort of 28 nonrenal patients (control group). There was no significant difference in gender, age, hip side, American Society of Anesthesiology (ASA) classification, comorbidities, and preoperative Harris score and hemoglobin (Hb) level between 2 groups ( P>0.05). The complications during hospitalization, Hb level changes, perioperative transfusion rate, hospital stay, and hospitalization costs in 2 groups were evaluated; and the creatinine changes of dialysis patients in ESRD group were evaluated. During the follow-up period, 90 days readmissions, periprosthetic infection, prosthesis loosening, hip Harris score, and deaths were recorded. There was no loss of follow-up. The mean postoperative follow-up of ESRD group was 3.4 years (range, 1.0-7.4 years) and control group was 3.5 years (range, 1.0-7.4 years). Differences in hospital stay and the drop of Hb was not significant between 2 groups ( P>0.05). The hospitalization costs and perioperative transfusion rate were significantly higher in ESRD group than in control group ( P<0.05). There was no significant difference in creatinine value of dialysis patients in ESRD group between pre- and post-operation ( t=1.804, P=0.089). At last follow-up, the Harris score was significantly higher than preoperative score in both groups ( P<0.05); however, there was no significant difference in Harris score between groups ( t=1.278, P=0.207). In ESRD group, 5 patients presented complications, 1 patient was readmitted to hospital, and 2 patients died during the follow-up. In control group, 1 patient presented complications, and there was no 90 days readmission and no death. During the follow-up period, there was no loosening or revision in 2 groups and the prosthesis was in good position. THA can improve joint function and life quality of ESRD patients, but the risks of operation, perioperative complications, transfusion rate, and cost are high. Correct perioperative evaluation and management can help ESRD patients safely go through the perioperative period.

  • Research Article
  • Cite Count Icon 122
  • 10.2106/jbjs.d.02097
Cementless Total Hip Arthroplasty and Limb-Length Equalization in Patients with Unilateral Crowe Type-IV Hip Dislocation
  • Feb 1, 2005
  • The Journal of Bone &amp; Joint Surgery
  • Kuo-An Lai + 3 more

Total hip arthroplasty in patients with unilateral congenital high dislocation of the hip (Crowe type IV) presents many challenges, including the problem of a marked limb-length discrepancy. The purpose of this retrospective study was to analyze the results of total hip replacement with limb-length equalization in these patients. From 1988 to 1996, fifty-six patients (forty-seven women and nine men) with unilateral Crowe type-IV dislocation of the hip were treated with a cementless total hip arthroplasty at a mean age of 35.4 years. The preoperative limb-length discrepancy averaged 4.9 cm. Prior to the total hip arthroplasty, forty-eight patients with a limb-length discrepancy of >4.0 cm underwent iliofemoral distraction with use of an external fixator for eight to seventeen days. The acetabular cup was placed in the anatomical position in every patient. Shortening femoral osteotomies were not required. The iliac fixator pins loosened in six patients. No patient had a pin-site infection, hip joint infection, or nerve palsy. At the time of follow-up, at an average of 147.2 months, the Harris hip score averaged 90.2 points. Overall, the mean lengthening after the total hip arthroplasty was 4.6 cm. There were no revisions of the femoral stem. Nine cups were revised, four because of polyethylene wear and five because of loosening. We were able to safely place the acetabular cup at the anatomical position without femoral shortening by bringing the femoral head to the normal level preoperatively; thus, we could restore nearly normal limb length. We believe that our twelve-year results are similar to those of total hip arthroplasty in patients without dysplasia.

  • Research Article
  • Cite Count Icon 2
  • 10.1055/s-0039-1692199
Early Total Hip Arthroplasty for the Treatment of Acetabular Fractures
  • Jun 27, 2019
  • The Journal of Hip Surgery
  • Michael C Willey + 2 more

Early total hip arthroplasty in patients with acetabular fractures is considered in rare situations with specific indications. Generally, this treatment option is considered in patients older than 55 or 60 years, but the physiological age must also be considered. The patient should be functional and ambulatory before the injury and healthy enough to tolerate the insult of a surgical procedure of this magnitude. Preexisting conditions such as osteoporosis and osteoarthritis encourage consideration of total hip arthroplasty. Specific injury patterns are predictive of fixation failure in older patients with acetabular fractures. These findings represent worse articular injury and low bone density that would intuitively lead to failure. This “gull sign” or “seagull sign” describes either the central–superior dome impaction seen in high-transverse fractures or the impaction of the subchondral bone on the intact edge of a partial posterior column fracture. Other radiographic predictors of failure in posterior wall fractures include comminution of more than three fragments, involvement of the superior dome in high posterior wall fractures, and marginal impaction. Older patients have a high incidence of these radiographic findings, predictive of fixation failure without arthroplasty. Other injury characteristics including concomitant displaced femoral neck fracture and femoral head injury are also indications for total hip arthroplasty in older patients. Acute hip arthroplasty can be performed using the posterolateral, direct lateral, anterolateral, and anterior approaches to the hip. There are also reports of patients who underwent combined approaches to the hip for stabilization of the injury using the anterior intrapelvic approach and ilioinguinal approach. Combined approaches are generally not recommended. Extended approaches are not recommended or necessary for early arthroplasty in acetabular fractures. This review article highlights recent trends of early total hip arthroplasty in senior patients with acetabular fracture, and the indications for the procedure, complications, clinical outcomes, and technical considerations, with cases to highlight these concepts.

  • Research Article
  • Cite Count Icon 39
  • 10.1016/j.arth.2017.11.063
The Cost-Effectiveness of Total Hip Arthroplasty in Patients 80 Years of Age and Older
  • Dec 5, 2017
  • The Journal of Arthroplasty
  • Samuel T Kunkel + 4 more

The Cost-Effectiveness of Total Hip Arthroplasty in Patients 80 Years of Age and Older

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  • Cite Count Icon 4
  • 10.3928/01477447-20221024-04
Midterm Results of Contemporary Uncemented Total Hip Arthroplasty in Patients 45 Years or Younger.
  • Oct 28, 2022
  • Orthopedics
  • Nicholas Hernandez + 4 more

Total hip arthroplasty (THA) in young patients has varying results, and some reports show inferior results when compared with those of older patients. This study evaluated the outcomes of contemporary uncemented THA in patients 45 years or younger. This was a retrospective review from 2003 to 2015 at an academic institution. Three hundred one uncemented THAs in 232 patients 45 years or younger were evaluated. All patients had a minimum follow-up of 5 years. Ninety-day complications, survivorship free of revision, and dislocations were evaluated. Mean age was 35.7 years, 43.1% of patients were women, and mean follow-up was 9.3 years. Ninety-day complications included 26 emergency department visits, 11 readmissions, 3 revisions, and 3 dislocations. The rate of 10-year survivorship free of revision was 85.5%, and the rate of 10-year survivorship free of aseptic revision was 87.7%. Excluding metal-on-metal (MOM) THAs, 10-year aseptic survivorship was 93.3%. The most common reasons for revision were adverse local tissue reaction after MOM THA (16 hips) and periprosthetic joint infection (6 hips). In a multivariable logistic regression model, sickle cell disease (SCD) and conversion THA were associated with 90-day readmissions. Both MOM THA and SCD were associated with revision (P<.05). Patients who are 45 years or younger undergoing THA (excluding MOM articulation) had a rate of 10-year survival free of aseptic revision of 93.3%. At 9.3 years' mean follow-up, THA in young patients was associated with low revision rates with acceptable risk of prosthetic joint infection and dislocation. Patients with SCD are at increased risk for early readmission and revision at latest follow-up. [Orthopedics. 2023;46(1):e45-e51.].

  • Research Article
  • Cite Count Icon 1
  • 10.3760/cma.j.issn.0376-2491.2016.11.011
Correlation between shifting of gravity center position and functional recovery after total hip arthroplasty in patients who suffered from avascular necrosis of the femoral head
  • Mar 22, 2016
  • Zhonghua yi xue za zhi
  • Julaiti Tayierjiang + 4 more

To explore correlation between shifting of gravity center position (GCP) and functional recovery after total hip arthroplasty (THA) in patients who suffered from avascular necrosis of the femoral head. Eighty six patients (49 right hip, 37 left hip) with avascular necrosis of the single femoral head who underwent THA at our department from January 2011 to December 2013 were investigated. Each patient was evaluated with Harris score system and measured GCP by corresponding instrument preoperatively and six month, one-year postoperatively. Pearson's correlation analysis was used to analyze the correlation between shifting degree of GCP and changing degree of Harris score at the above time points. Harris score significantly improved after surgery (P<0.01), and there was a direct linear relationship between shifting degree of GCP and changing degree of Harris score at the same period after the surgery, and the adjusted R(2) value between them were 0.521 at six month and 0.46 at one year after operation. As the function of the hip recovers, the GCP moves from its initial position to the operative side after THA. The shifting degree of GCP can be a reflection of recovery of the joint function in some extent.

  • Research Article
  • 10.1007/s00264-026-06860-w
Patient-reported outcomes of transposition osteotomy of the acetabulum and contralateral total hip arthroplasty in patients with bilateral hip dysplasia.
  • May 18, 2026
  • International orthopaedics
  • Masanori Fujii + 6 more

To clarify differences in hip-specific function, satisfaction, and patient preference between transposition osteotomy of the acetabulum (TOA) and contralateral total hip arthroplasty (THA) in the same patients with bilateral hip dysplasia. Among 689 patients who underwent TOA between 1998 and 2019, 32 patients who also underwent contralateral THA were included. Median age at surgery was 46 years for TOA and 50 years for THA (p = 0.008), and median follow-up was 14 and 12 years, respectively (p = 0.049). Postoperative patient-reported outcome measures included pain and satisfaction visual analogue scales (VAS), the Forgotten Joint Score-12 (FJS-12), and the Hip disability and Osteoarthritis Outcome Score (HOOS). Patients were also asked which hip they preferred. Preoperative modified Harris Hip Score (mHHS) was higher in TOA hips than in THA hips (64 vs. 43; p < 0.001), whereas the latest mHHS was lower in TOA hips (92 vs. 96; p = 0.007). Although pain VAS, FJS-12, and all HOOS subscales were comparable between TOA and THA, satisfaction VAS was higher in THA hips (98 vs. 93; p = 0.029). Fifteen patients (47%) preferred THA, nine (28%) reported no difference, and eight (25%) preferred TOA. The most common reason for preferring THA was less pain (10 of 15 patients, 67%). In middle-aged patients with bilateral hip dysplasia, TOA and contralateral THA yielded comparable functional outcomes; however, satisfaction was higher after THA, and 47% preferred THA. These findings may inform shared decision-making regarding joint-preserving surgery and arthroplasty.

  • Research Article
  • Cite Count Icon 12
  • 10.1016/j.jcot.2017.05.004
Birmingham hip resurfacing versus cementless total hip arthroplasty in patients 55 years or younger: A minimum five-year follow-up
  • May 23, 2017
  • Journal of Clinical Orthopaedics and Trauma
  • Mohamad J Halawi + 5 more

Birmingham hip resurfacing versus cementless total hip arthroplasty in patients 55 years or younger: A minimum five-year follow-up

  • Research Article
  • Cite Count Icon 33
  • 10.1007/s00402-017-2741-8
Systematic review of the outcome of total hip arthroplasty in patients with sequelae of Legg-Calvé-Perthes disease.
  • Jul 3, 2017
  • Archives of orthopaedic and trauma surgery
  • Sammy A Hanna + 3 more

Total hip arthroplasty (THA) in patients with sequelae of Legg-Calvé-Perthes disease (LCP) is technically demanding because of the disease related deformities occuringin the proximal femur and/or themultiplanar deformities secondary to corrective osteotomies in childhood. Little is known about the long-term outcome of the procedure in this challenging group of patients. We carried out a systematic review of the literature to determine the functional outcome, complications and revision rate of THA in patients with sequelae of LCP disease. Six out of 148 potential studies involving 245 hips met the inclusion criteria. The mean age was 45.7years (19-74) and follow-up was 8.4years (2-21). There were 221 cementless THAs (90%), 22 hybrid THAs (9%) and 2 cemented THAs (1%). The femoral components used included 187 standard stems (76%), 43 modular stems (18%) and 15 custom-made stems (6%). The modular implants used were reamed S-Rom stems. All studies reported a significant improvement in hip function following THA. There were 16 revision THAs (7%) occurring at a mean of 7.5years (0.4-10.3). Complications included intra-operative fracture (11%, n=27), aseptic loosening (5%, n=13), sciatic nerve palsy (3%, n=7) and heterotopic ossification (2%, n=4). All intra-operative fractures occurred when standard femoral stems were used. The average limb lengthening in the patients with a post-operative sciatic nerve injury was 1.9cm. All patients with this complication had a history of previous hip surgery. THA in patients with LCP disease results in similar functional outcome compared to patients with primary osteoarthritis; however, the revision rate at mid-term follow-up is slightly increased. Reamed modular (S-Rom) and custom femoral implants appear to be associated with a decreased risk of intra-operative fracture. Care should be taken when addressing leg length discrepancy in this group of patients due to the increased risk of sciatic nerve palsy, especially in patients with prior surgical procedures.

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  • Research Article
  • Cite Count Icon 4
  • 10.3390/jcm8101703
Outcomes of Total Hip Arthroplasty in Patients with Osteonecrosis of the Femoral Head Following Surgical Treatment of Brain Tumors.
  • Oct 16, 2019
  • Journal of Clinical Medicine
  • Seung-Jae Lim + 7 more

Corticosteroids have been widely used in patients with brain tumors to reduce tumor-associated edema and neurological deficits. This study examined the outcomes of total hip arthroplasty (THA) in patients with osteonecrosis of the femoral head (ONFH) following brain tumor surgery. We identified 34 THAs performed in 26 patients with steroid-induced ONFH among 9254 patients undergoing surgical treatment for primary brain tumors. After propensity score matching with demographics, 68 THAs (52 patients) in ONFH unrelated to brain tumors were selected as the control group. At the time of THA, 54% of brain tumor patients had neurological sequelae and 46% had adrenal insufficiency. After THA, patients with brain tumor required longer hospital stay, reported a lower functional score, and showed a higher rate of heterotopic ossification compared to the control group. However, hip pain score improved significantly after THA in the brain tumor group, and did not differ from that of the control group (P-value = 0.168). Major complication rates were similar (2.9% and 1.5% for the brain tumor and control groups, respectively; P-value = 1.000), and implant survivorships were not different at 7 years (100% and 98.1% for the brain tumor and control groups, respectively; P-value = 0.455). Our findings suggest that THA can be safely performed to reduce hip pain in patients with steroid-induced ONFH after surgical treatment of primary brain tumors.

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