Abstract
period compared with the preoperative period (P < .001). Patients with CLI operated on with bypass had a fivefold increase in the rate of 30-day postoperative antibiotic prescription compared with the preoperative period (IRR, 5.5 [4.8-6.4]; P < .001). Patients undergoing endovascular interventions had a 52% increase in the rate of dispensed antibiotic prescriptions postoperatively, compared with the preoperative period (IRR 1.5 [1.7-1.9]; P < .001), related to an increase in the incidence of UTI antibiotics (P < .001). Thirty-two percent (1067 of 3294) of patients with postoperative antibiotics had received an antibiotic prescription during the month leading to the index operation. UTI antibiotics dominated the postoperative 30-day period for claudicant patients (P < .001), as opposed to skin and soft tissue antibiotics, which were prominent in the ulceration/gangrene group (P < .001). Conclusions: Antibiotic treatment can be a useful marker for postoperative infections in vascular surgery patients. The incidence of postoperative HCAI in these patients has previously been underestimated. This highlights the need for comprehensive postdischarge follow-up regimens.
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