Frequency of extra articular manifestations in ankylosing spondylitis patients presented at independent university hospital Faisalabad.

Abstract

Objective: To determine the frequency of extra articular manifestations in Ankylosing spondylitis patients at Independent University Hospital Faisalabad. Study Design: Cross-sectional study. Setting: Rheumatology Division of Internal Medicine Independent University Hospital, Faisalabad. Period: June 2020 to June 2021. Material & Methods: Consecutive one hundred and thirty-nine adult patients with baseline Ankylosing Spondylitis fulfilling the Assessment of spondyloarthropathy society criteria at early stage and Modified New York criteria in chronic form of disease, and fulfilling the selection criteria, were selected through Non-Probability Convenient Sampling technique for this study. Chi square test was used to compare the frequency of extra articular manifestations among disease duration, age groups and treatment group. A p-value ≤ 0.05 was considered statistically significant. Results: In this study, 139 number of patients were selected with confirmed diagnosis of ankylosing spondylitis. Mean age of patients was 32.60 ± 8.5 years with age range of 18 to 50 years. Extra articular manifestations were assessed in all selected patients of ankylosing spondylitis. Enthesitis and dactylitis were found in 8.6% (12) of patients. Uveitis was found in 5% (7) of patients. Similarly, psoriasis was found in 4.3% (6) of patients. Lung fibrosis was found in 3.6% (5) of patients. Inflammatory bowel disease was found in 2.9% (4) of patients. Conclusion: Assessment of extraarticular manifestations in AS was very important. Timely intervention with specific therapy decreases morbidity and mortality related to disease.