Abstract

Frequency of expression and the distribution of ABO and Rh, Blood group antigens in the myocardial infarction (MI) male Patients of the Hail region in Saudi Arabia

Highlights

  • According to the recent world health organization (WHO) survey 17.5 million people die every year due to cardiovascular disease (CVD) making it about 31% of all the global deaths, 80% of these deaths occur due to myocardial infarctions (MI) and strokes (WHO Media Centre, 2016)

  • We wanted to look at some of the risk factors which are known to be associated with coronary heart disease (CHD), such as smoking habits, hypertension and diabetes in the control population

  • Since it is already established that the blood groups are the major determinants of von Willebrand factor (VWF) levels and since high VWF is considered as one of the major risk factors for thrombosis [14,15] and since previous studies have not been consistent about the specific blood groups and their possible association with the plasma levels of VWF and factor VIII, and since CHD is the leading cause of death in Saudi Arabia, we decided to look at possible correlation and association between the CHD and inheritance of ABO and Rh antigens in the Saudi population

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Summary

Introduction

According to the recent world health organization (WHO) survey 17.5 million people die every year due to cardiovascular disease (CVD) making it about 31% of all the global deaths, 80% of these deaths occur due to myocardial infarctions (MI) and strokes (WHO Media Centre, 2016). According to the same survey 75% of the CVD related deaths occur in the countries with low or middle income. Due to the seriousness of this issue and its toll on global population, on September 22nd, 2016, WHO launched “Global Hearts” initiative to fight back CVDs including the cases of stroke and heart attacks. According to the WHO world health ranking survey Saudi Arabia ranked 27th in coronary heart disease (CHD) related deaths. CHD was the leading cause of deaths in Saudi Arabia (WHO, 2014 survey) [1]. One of the major reasons for CHD is tobacco use (WHO bulletin 2016) and the rapidly rising cases of obesity in Saudi Arabia [2,3] due to consumption of unhealthy diet, lack of exercise or any other physical activity [3]

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