Abstract
SUMMARY The total cholesterol content and the proportions of free and esterified cholesterol have been determined in the cerebrospinal fluid and sera of goats during the onset of experimental scrapie. The total cholesterol in cerebrospinal fluid remained relatively constant but a small rise occurred in clinically affected animals. The proportions of free cholesterol increased in all goats when only slight histological damage to brain tissue was present. The mean value for the total cholesterol was 4·0 mg./l. in the experimental animals and, of this, 48 % was free cholesterol when terminal elevations were ignored. In sera there were periodic fluctuations during 12 months in the total cholesterol content which were associated with rises in the proportions of free cholesterol. The mean value for total cholesterol in serum was 70 mg./ 100 ml. and, of this, free cholesterol on an average was 58 %.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
