Abstract
Evolutionary game theory has been widely used to simulate tumor processes. Inter-cellular interactions that occur within tumor populations are good examples of biological evolutionary games for space and nutrients. Presented extended model considers four strategies (phenotypes) that can arise by mutations: cells that produce harming substances to gain advantage, cells resistant to these substances, cells that produce growth factor which affects any other cell-kinds and neutral cells. Different equilibrium points, scenarios and spatial versions are also discussed..
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