Abstract
Two novel resveratrol trimers, amurensins C ( 1), D ( 2), and two novel resveratrol pentamers, amurensins E ( 3), F ( 4) were isolated from the roots of Vitis amurensis Rupr. Their structures and relative or absolute configurations were determined by means of spectroscopic evidence, especially HMBC and NOE experiments. 2, 3 and 4 are new types of resveratrol oligomers and are reported here for the first time. The pharmacological activities on anti-inflammation of all amurensins have been tested. Among them, compound 4 showed potent inhibition on biosynthesis of leukotriene B 4 (LTB 4).
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