Abstract
AbstractN‐(3‐Aminothioacryloyl)‐formamidines 3 react with primary amines to give either 4(1H)‐pyrimidinthiones 6 or transaminated N‐(3‐aminothioacryloyl)‐formamidines 5. Alkylation of the latter compounds gives rise to cyclised 6(1H)‐pyrimidinimines 7. The 4(1H)‐pyrimidinthiones 6 can be S‐alkylated to 4‐alkylmercaptopyrimidinium salts 8. Subsequent substitution of the alkylmercapto group of the 8 results in the formation of 4‐aminopyrimidinium salts 9, which can also be obtained starting from the 3 by a reversed reaction sequence that is first by S‐alkylation to 3‐alkylmercapto‐2‐azapentamethinium salts 10 and subsequent reaction with primary amines.
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