Formulation and Evaluation of Micro Beads of Clonidine for the Treatment of Anxiety and Hypertensive Disorder

Abstract

A chronic medical condition known as hypertension (HT) is characterised by persistently high blood pressure (BP) in the arteries. Although HT is initially asymptomatic, it eventually develops into a significant risk factor for renal, cardiovascular, and cerebrovascular conditions, which in turn are major contributors to morbidity and mortality in industrialised nations. A complicated disorder called HT is thought to affect more than one-fourth of adult humans worldwide. Both its pathophysiology (primary and secondary HT) and the measurements of the resting blood pressure (elevated systolic, diastolic, and pulse pressure) are used to categories it. It results from a complex interplay between genes and a number of environmental risk factors, including as ageing, smoking, inactivity, being overweight or obese, eating too much salt, stress, depression, and anxiety. Millions of people are affected by anxiety and depressive disorders each year, which are the most often diagnosed mental illnesses. These conditions are both characterised by emotional, cognitive, psychomotor, and neurovegetative symptoms. Additionally, stress at work has been identified as a significant risk factor for heart disease (CVD) and HT. Despite the fact that numerous writers have looked into and proposed connections between HT, stress, anxiety, and depression over the past few decades, a complete knowledge of the underlying pathophysiological mechanisms has not yet been attained, particularly with regards to young people. The purpose of this study was to examine the role that stress and anxiety from the workplace play in the HT development of young students of health care professions as well as any potential links to early CVDs.
 Keywords: Blood pressure, Anxiety, Work-related stress, Students, Health care professions, Health promotion, Workplace, Occupational medicine