Abstract
Many freshly created high-potential medications have low water solubility, which is a challenge in formulation development. The study aimed to improve the solubility of Lamotrigine, a weakly soluble medication classified as BCS class II, by solid dispersion techniques. Lamotrigine solid dispersion was created using the solvent evaporation method, and the formulation was assessed using stability tests, Fourier transform infrared spectroscopy (FTIR), and physical properties. Preformulation investigations yielded satisfactory results, therefore pellets were formed and evaluated. Solid dispersion had a different pharmacokinetic profile than pure medication, which could be attributable to Lamotrigine's faster dissolution rate from solid dispersion
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal For Multidisciplinary Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
