Abstract
Using X-ray diffraction analysis, transmission electron microscopy, and complex thermal analysis, it was shown that brushite crystals are formed from aqueous solutions of ammonium hydrogen phosphate and calcium nitrate. The hydrothermal treatment of brushite results in the formation of quasi-one-dimensional hydroxyapatite nanoparticles, the longitudinal size of which is about 400 nm, and the transverse size is 40 nm. It was demonstrated that hydroxyapatite nanoparticles can be used as fillers of composite matrices for tissue engineering, in particular, in bone grafting.
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