Abstract
Like other SLRPs, lumican has a molecular weight of ~40 kDa comprised of four major domains: (1) a signal peptide of 16 residues; (2) a negatively charged N-terminal domain containing sulfated tyrosine and disulfide bond(s); (3) tandem leucine-rich repeats (LXXLXLXXNXLSXL)10 mediating binding to other extracellular components, e.g. collagen; (4) a carboxyl terminal domain of 50 amino acids containing two conserved cysteines 32 residues apart.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.