Abstract
This study is a prospective trial comparing the incidence of post-operative complications to fluid status in patients undergoing coronary artery bypass grafting (CABG) surgery. One hundred and nine subjects undergoing CABG surgery at the Jewish general hospital were recruited over a 5 months period in the year 2006. All of the patients underwent CABG surgery “on pump”. Post operative fluid overload was measured by weight gain. Using logistic regression with complications (major vs. minor only/none) as an outcome and fluid overload as a covariate, the risk of major complications significantly increases for fluid overload ≥5 kg compared to 1 - 5 kg (p < 0.001), while the risk for ≤1 kg is not significantly different from 1 - 5 kg. Also, the risk of major complications significantly (p = 0.012) increases for days with fluid overload ≥5 days in comparison to ≤1 day.
Highlights
Looking at the relationship between demographic factors and complications, we found that the median age of patients with major, minor or no complications was similar at 62 years old
For patients with major complications, 43.36% were in NYHA class III or IV compared to 0% in NYHA class I or II
Open heart surgery is associated with a degree of fluid overload
Summary
Open heart surgery requiring cardio-pulmonary bypass (CPB) has been well known to result in post-operative fluid overload. Our present proposed study is a prospective trial comparing the frequency of post-operative complications to fluid status in patients undergoing coronary artery bypass grafting (CABG) surgery. The average amount of fluids given intra-operatively, including pump prime, cardioplegia, crystalloids, colloids, blood transfusions and blood derived products was. The average amount of fluids given post-operatively up to 24 hours, including crystalloids and colloids, blood transfusions and blood derived products was 3240.04 mL. Post-operative fluid overload was measured by weight gain, which was measured on a ScaleTronix electronic scale on each day in the hospital after surgery for eight days and compared to pre-operative weight. Statistical calculations were carried out using Stata statistical software (Intercooled Stata v8.2, College Station, TX, StataCorp)
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