Abstract
The accumulation of cells characteristic of neoplastic disease results from the combination of unrestrained cell growth and diminished cell death. One form of programmed cell death, apoptosis (a Greek neologism meaning “dropping off” that conjures images of leaves falling from a tree in autumn), is an important mechanism of normal cellular population control (1). Cells that are physiologically unwanted (e.g., auto-reactive lymphocytes) and cells that have suffered irreversible DNA-damaging injury (e.g., from ultraviolet light or irradiation) may be eliminated via apoptosis. Cytoreductive antineoplastic therapy operates in part by triggering apoptosis of susceptible cells (2,3).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
