Abstract
In the first detailed study of the flavonoid pattern of Achillea roseo-alba rutin, apigenin-7-O-ß-glucopyranoside, luteolin-7-O-ß-glucopyranoside, isorhamnetin-3-O-rutinoside, schaftoside, luteolin-4’-O-ß-glucopyranoside and 6-OH-luteolin-7-O-ß-glucopyranosid were proven in the methanolic extract of aerial parts of the plant. Additionally quercetin-3-O-[ß-apiofiranosyl-(1′′′→2′′)-ß-glucopyranoside] was identified for the first time in the genus Achillea.
Highlights
Several species from the genus Achillea are used traditionally as aromatic bitters with adstringent, choleretic and anti-inflammatory activities [I].Different studies [2,31 showed that the anti-inflammatory effect is attributed to the presence of sesquiterpene lactones, and to flavonoids
Within chemotaxonomic investigations of the Achillea millefoIium aggregate the flavonoid complex of the tetraploid species Achillea collina BECKER [4]and the octoploid species Achillea pannonica SCHEELE [ 5 ] had been studied in detail
The object of this study was the flavonoid pattern of diploid Achillea roseo-alba EHREND
Summary
Several species from the genus Achillea are used traditionally as aromatic bitters with adstringent, choleretic and anti-inflammatory activities [I].Different studies [2,31 showed that the anti-inflammatory effect is attributed to the presence of sesquiterpene lactones, and to flavonoids. Until now only the flavonol glycoside rutin had been identified from this species [6].The present communication describes the isolation of eight flavonoid glycosides from a methanolic extract of Achillea roseo-alba. The fractionation of the purified methanolic extract of aerial parts of Achzllea roseo-alba was performed by CC on polyamide and SephadexB LH-20 using gradient elution with HzOMeOH mixtures.
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