Abstract

AbstractPurpose To determine retinal and systemic risk associations of branch retinal vein occlusion (BRVO) over 5 years in adult population‐based cohort in Japan.Methods The Funagata study is a population‐based longitudinal cohort study in Yamagata, Japan. In 2000‐2, we performed baseline survey including fundus photography and systemic examination. In 2005‐7, 5‐year follow‐up survey was performed and newly developed BRVO cases were determined. There were 954 persons who attended both baseline and 5‐year follow‐up survey; 878 persons had good quality fundus photographs suitable for grading (right eye only). Using multiple logistic regression models, retinal and systemic risk characteristics were determined.Results Mean age of study participants were 58.9 years old and 57.2% were women. Prevalence of diabetes and hypertension was 4.0% and 32.2%, respectively. There were 12 newly developed BRVO over 5‐ years (1.37%, right eyes only). In multiple logistic regression models including those significantly associated systemic risks, older age (adjusted odds ratio [OR] 1.15 per 1 year, 95% confidence interval [CI] 1.02‐1.31, p=0.026) and waist‐to‐hip ratio (adjusted OR 6.15 per 0.1, 95%CI 1.50‐25.3, p=0.012) remained as significant risk characteristics. Retinal vessel opacification was significantly associated with incident BRVO after adjusting for systemic risk characteristics.Conclusion In addition to older age, larger waist‐to‐hip ratio was identified as a modifiable systemic risk characteristic of 5‐year incident BRVO. Retinal vessel opacification was also identified as a risk characteristic in the retina; there is a potential as a marker to predict BRVO. Commercial interest

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.