Abstract

Oxyphilic cell tumors of the thyroid are relatively rare which consist of large cells characterized by marked cytoplastic acidophilia. In this paper recent 5 cases of oxyphilic cell tumor of the thyroid were clinically studied.The tumors represented 2.4% of all primary thyroid tumors, and the patients comprised females only with an age ranging from 38 to 66 years (mean 53.8 years). They complained of an anterior neck tumor without compression symptoms, and had normal thyroid function. Preoperative examinations such as neck X-ray, ultrasonography and scintigram could not make a definite diagnosis. Enucleation was carried out in 2 cases and lobectomy in 3 cases. The cellular differentiation between benign and malignant types of the tumors is very difficult, and we used diagnostic criteria for malignancy including capsular or vascular invasion. There were 4 cases of oxyphilic cell adenoma and 1 case of oxyphilic cell carcinoma. The patients have been in good condition and no recurrence can be found.

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