Abstract
Abstract Introduction: Natural orifice translumenal endoscopic surgery (NOTES) is moving into the clinical arena with multiple feasibility trials taking place around the world. Early results appear encouraging, and the transvaginal access route appears most favoured due to its established safety parameters in gynecological surgery. Following extensive simulator, ex vivo, in vivo, and clinical research and following a successful trial of hybrid NOTES cholecystectomy, ethical approval was granted to evaluate the feasibility and clinical outcomes of transvaginal NOTES-assisted sigmoid colectomy at Imperial College. Methods: A 63-year-old woman who had been admitted to hospital on three occasions with radiologically confirmed diverticulitis was counseled for inclusion in the trial. The patient had previously undergone laparoscopic sterilization, but had no major cardiopulmonary comorbidities. Results: On the 24th of February 2012, the patient underwent the first UK transvaginal NOTES-assisted sigmoid colectom...
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