Abstract
INTRODUCTION: The aac(6’)-Ib-cr and bla KPC genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world. METHODS: These genes were investigated in 28 P. stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by PCR and sequencing. RESULTS: The aac(6’)-Ib-cr gene was detected in 16 resistant isolates, and the bla KPC gene was seen in 14.CONCLUSIONS: The presence of these genes in P. stuartii multi- and extensively drug-resistant isolates indicates that the resistance arsenal of this species is increasing, thus limiting the therapeutic options.
Highlights
Introduction: The aac(6’)-Ib-cr and blaKPC genes are spreading among Enterobacteriaceae species, including Providencia stuartii, in some countries of world
These genes were investigated in 28 P. stuartii isolates from a public hospital in Recife, Pernambuco, Brazil, by polymerase chain reaction (PCR) and sequencing
The aac(6’)-Ib-cr gene was detected in 16 resistant isolates, and the blaKPC gene was seen in 14. The presence of these genes in P. stuartii multi- and extensively drug-resistant isolates indicates that the resistance arsenal of this species is increasing, limiting the therapeutic options
Summary
First report of the aac(6’)-Ib-cr gene in Providencia stuartii isolates in Brazil. Sivoneide Maria da Silva[1], Bárbara de Azevedo Ramos[1], Ana Vitória Araújo Lima[1], Rafael Artur Cavalcanti Queiroz de Sá[1], Jailton Lobo da Costa Lima[2], Maria Amélia Vieira Maciel[2], Patrícia Maria Guedes Paiva[1], Márcia Vanusa da Silva[1], Maria Tereza dos Santos Correia[1] and Maria Betânia Melo de Oliveira[1]. Universidade Federal de Pernambuco, Centro de Biociências, Departamento de Bioquímica, Recife, PE, Brasil. Universidade Federal de Pernambuco, Centro de Ciências Médicas, Departamento de Medicina Tropical, Recife, PE, Brasil
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