Abstract
ABSTRACTFirst Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers. Anna Gray is first author on ‘ Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice’, published in DMM. Anna conducted the research described in this article while a PhD student in Prof. Linda Greensmith's lab at the Department of Neuromuscular Disease, UCL Institute of Neurology, Queen Square, London, UK. She is now a postdoctoral research associate in systems neurobiology in the lab of Prof. Rasmus Petersen at the Division of Neuroscience & Experimental Psychology, Faculty of Biology, Medicine & Health, University of Manchester, UK, investigating the development of reliable in vivo techniques to study neurobiology in health and disease.
Highlights
What are the potential implications of these results for your field of research? Spinal and bulbar muscular atrophy (SBMA) is a genetic disorder caused by a trinucleotide repeat expansion in the gene that encodes the androgen receptor (AR)
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers
How would you explain the main findings of your paper to non-scientific family and friends? Spinal and bulbar muscular atrophy (SBMA), known as Kennedy’s disease, is a neuromuscular disease characterised by loss of motor neurons in the spinal cord, which control muscle function, with accompanying muscle weakness and wasting
Summary
What are the potential implications of these results for your field of research? SBMA is a genetic disorder caused by a trinucleotide repeat expansion in the gene that encodes the androgen receptor (AR). First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms (DMM), helping early-career researchers promote themselves alongside their papers. Anna Gray is first author on ‘Deterioration of muscle force and contractile characteristics are early pathological events in spinal and bulbar muscular atrophy mice’, published in DMM.
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