Abstract
Fever of unknown origin (FUO) can be caused by tumors, especially those arising from the hematopoietic system. Multiple myeloma can also cause fever but it is not a common cause of fever of unknown origin. We report a 53 year-old man presenting with fever lasting eight weeks. An extensive study for common causes of FUO was negative. The appearance of hypercalcemia and proteinuria during the evolution suggested the presence of a multiple myeloma, that was confirmed with a bone marrow biopsy. Thalidomide and dexametasone were prescribed with resolution of fever.
Highlights
Fever of unknown origin (FUO) can be caused by tumors, especially those arising from the hematopoietic system
We report a 53 year-old man presenting with fever lasting eight weeks
Creemos que nuestra comunicación es interesante, porque existen pocos casos publicados de pacientes con mieloma múltiple (MM) que se presenta como FOD, pudiendo motivar a considerar más formal y precozmente esta entidad en el diagnóstico diferencial de estos pacientes
Summary
Fever of unknown origin (FUO) can be caused by tumors, especially those arising from the hematopoietic system. Actualmente las etiologías neoplásicas son menos frecuentes como causa de FOD, probablemente debido a una pesquisa más precoz facilitada por el desarrollo de los estudios de imagen. El mieloma múltiple (MM) infrecuentemente se presenta con fiebre, y cuando lo hace, generalmente obedece a una infección viral o bacteriana sobreagregada[3,4,5], por ello no suele ser considerado como causa de FOD.
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