Abstract
AbstractFibrous dysplasia is a disease in which fibrous tissues replace the normal bone medullary space. Monostotic fibrous dysplasia accounts for 70–85% of cases of fibrous dysplasia and develops in areas such as the rib and femur. Polyostotic fibrous dysplasia accounts for 15–30% of cases and develops in areas such as the femur and tibia. Bone scan is a valuable imaging technique for differentiating between monostotic and polyostotic fibrous dysplasia and mostly shows the area of intensely increased uptake. Bone scan can be useful for assessing the activity of fibrous dysplasia because the uptake decreases in the quiescent state. Fibrous dysplasia requires a differential diagnosis with other diseases because small lesions can show false-negative results. Bone SPECT/CT can be used to accurately determine the extent of disease invasion. 18F-FDG PET/CT shows variable uptake for fibrous dysplasia.KeywordsFibrous dysplasia of boneFibrous dysplasia, monostoticFibrous dysplasia, polyostoticRadionuclide imagingSingle-photon emission computed tomography/computed tomographyPositron emission tomography/computed tomography
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