Abstract
Recently, we have proposed a refractive-index(RI)-sensing optical comb by placing a multi-mode interference (MMI) fiber sensor inside a fiber comb cavity. In this method, change of RI is read out as a repetition frequency frep via photonic RF conversion, and is precisely measured based on a RF frequency standard. If a surface of the intracavity MMI sensor is chemically modified for biosensing, it will be further used for biosensing. In this paper, we chemically modified the surface of the intracavity MMI fiber sensor with biotin and then read the chemical reaction with avidin as a change in frep.
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