Abstract

Pharmacogenomics (PGx) refers to how genetic variation can impact response to medications. It has great potential for clinical application as over 350 drugs have FDA approved PGx information in their labeling and 85-95% of the population will have an actionable PGx variant. Given the paucity of information about application and utility of PGx in prenatal testing, we reviewed fetal PGx data and the potential clinical implications in medically-complex neonates.

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