Abstract

Fetal growth retardation complicates an average of 10% of all pregnancies. Today, ultrasound examination is used in obstetrics for diagnosis. Therefore, early detection of this complication is the key to adequate treatment and reduction of perinatal consequences. A deeper understanding of the early accompanying ultrasound parameters will allow timely detection or prevention of intrauterine fetal development. The aim of the research was to conduct an ultrasound antenatal examination of women with intrauterine growth retardation. Ultrasound fetometry and placentometry were conducted in women with intrauterine growth retardation (the main group, n-41) and women in the comparison group with the physiological course of pregnancy (n-12). At the initial ultrasound examination, among women in the main group, fetuses below the 10th percentile were probably more common and had a decrease in biparietal head size and abdominal circumference (p = 0.001, p = 0.08). With repeated ultrasound examination, the frequency of detecting decreased indicators of biparietal head size, head circumference, abdominal circumference, femoral shaft length below the 10th percentile among women in the main group increases by 1.5 times, and significantly differs from the indicators of the comparison group. (p = 0.0002, p = 0.001). A decrease in the biophysical profile of the fetus to 6-7 points accompanies 63.4% of pregnancies with intrauterine growth retardation. The amniotic fluid index below the 5th percentile in relation to the gestational age in women at the initial examination was 2.4%, and at the second examination - 7.3%. The placental ultrasound marker of premature maturation by gestational age 21.4%, the presence of petrification in 58.5%. In case of timely detection of the fetometric and placentometric changes, it is possible, from the standpoint of modern obstetrics, to start etiopathogenetic therapy and prevention of this complication of pregnancy.

Highlights

  • IntroductionПри повторному ультразвуковому обстеженні зростає у 1.5 рази частота виявлення знижених показників біпарієтального розміру голови, обвіду голови, обвіду живота, довжини діафіза стегнової кістки нижче 10 процентилі серед основної групи, дані зміни є вірогідно відмінними від показників групи порівняння

  • The study was conducted in the frame of the research project of the Department of Obstetrics and Gynecology No.1 of Ukrainian Medical Stomatological Academy "Pathogenetic role of endothelial dysfunction and genetic features of pathology in pregnancy and gynecological diseases"

  • Ultrasound fetometry and placentometry were conducted in women with intrauterine growth retardation and women in the comparison group with the physiological course of pregnancy (n-12)

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Summary

Introduction

При повторному ультразвуковому обстеженні зростає у 1.5 рази частота виявлення знижених показників біпарієтального розміру голови, обвіду голови, обвіду живота, довжини діафіза стегнової кістки нижче 10 процентилі серед основної групи, дані зміни є вірогідно відмінними від показників групи порівняння. A deeper understanding of the early accompanying ultrasound parameters will allow timely detection or prevention of intrauterine fetal development. The aim of the research was to conduct an ultrasound antenatal examination of women with intrauterine growth retardation. Ultrasound fetometry and placentometry were conducted in women with intrauterine growth retardation (the main group, n-41) and women in the comparison group with the physiological course of pregnancy (n-12). Fetal intrauterine growth retardation (IUGR) and its subsequent adequate vital activity are associated with the diagnostic prediction of complications during pregnancy. A better understanding of the early concomitant ultrasound parameters will allow for the timely detection or prevention of fetal IUGR

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