Abstract
Nanoscale magnetite (Fe3O4) and nanocomposite based on it (Fe3O4/SiO2) were synthesized. In the model physiological solution [0.9% NaCl solution (NSS)], the acid–base properties of the surface were potentiometrically investigated. Also the size and morphology transmission electron microscopy, surface (FTIR spectroscopy) and magnetic properties vibration magnetometer, specific surface area were investigated for the synthesized samples. The adsorption processes were studied and the high-adsorption activity of the Fe3O4 nanoparticles (MNPs) surface with respect to Ig was established in the model physiological environment and phosphate buffer at pH 6.86 [maximum adsorption capacity (Amax) 24.54 mg/g]. The analysis of kinetic dependences and Ig adsorption isotherms using mathematical models that take into account the chemical interaction in the system indicates the monomolecular nature of adsorption (Langmuir and Freundlich models). Due to their high biocompatibility, the obtained MNPs with immobilized Ig can be potentially suitable as adsorption materials for the creation of biosensors and targeted drug delivery.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
