Abstract
At the time of diagnosis, patients with pancreatic cancer often have locally advanced disease, either alone or associated with small liver metastases. These patients suffer from local complications, including pain and biliary or intestinal obstruction. Survival in this group of patients is poor, with a median life expectancy of 8 - 12 months for patients with locally advanced and unresectable disease and only 3 - 6 months for those with metastatic disease at presentation [1]. Historically, patients with locally advanced disease have been treated with chemotherapy and radiation to the pancreatic bed, but the prognosis of the patients remains poor.
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