Abstract

Post-Polio Syndrome (PPS) is characterized by the appearance of new muscular symptoms or worsening of previous residual symptoms, several years after the acute polio. The most common symptoms include a trial of fatigue, deterioration in muscle strength and pain. Fatigue is one of the most frequent complaints of PPS and the majority of patients identify fatigue as their most troubling symptom. The aetiology of the symptom arouses great interest, mainly due to its multifactorial character, and can be divided into two components: peripheral (muscular) fatigue and central (general) or simultaneously-occurring fatigue. Considering the importance of the symptom and the limitations that can cause in PPS patients, it is important to consider a series of variables, so that it can be better understood, thus providing a more effective and specific treatment.

Highlights

  • Post-Poliomyelitis Syndrome (PPS) is characterized by a range of lateonset neuromuscular symptoms such as joint and muscular pain, new or increased muscle weakness and abnormal fatigability as key symptoms (Rowland et al, 2000; Motta et al, 2018).Among the symptoms of PPS, fatigue is one of the most frequent and is probably the main symptom

  • Viana et al (2013) reported that fatigue is more intense in the afternoon for patients with poliomyelitis sequelae and worsens progressively in patients with PPS

  • It is important to differentiate between physical fatigue, and decreased endurance associated with new weakness and central fatigue

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Summary

Introduction

Post-Poliomyelitis Syndrome (PPS) is characterized by a range of lateonset neuromuscular symptoms such as joint and muscular pain, new or increased muscle weakness and abnormal fatigability as key symptoms (Rowland et al, 2000; Motta et al, 2018).Among the symptoms of PPS, fatigue is one of the most frequent and is probably the main symptom. Occurring in about 60%-89% of individuals with PPS, it is one of the least studied symptoms (Bruno et al, 1994, 1995; Trojan et al, 1994, 2005). Conde et al (2009) pointed out that fatigue in patients with PPS is not related to a period of the day, but to the type of activity performed.

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