Abstract

In August 2018, a fatal autochthonous case of Crimean-Congo hemorrhagic fever was confirmed in western Spain. The complete sequence of the viral genome revealed circulation of a new virus because the genotype differs from that of the virus responsible for another case in 2016. Practitioners should be alert to possible new cases.

Highlights

  • In August 2018, a fatal autochthonous case of Crimean-Congo hemorrhagic fever was confirmed in western Spain

  • Diagnostic testing was performed by using a RealStar CCHFV RT-PCR Kit 1.0 (Altona Diagnostics, https://altona-diagnostics. com), and CCHFV infection was confirmed by 2 methods: reverse transcription PCR [1] and a nested reverse transcription PCR [2]

  • Phylogenetic analysis of the virus responsible for a fatal case of Crimean-Congo hemorrhagic fever (CCHF) in 2018 showed reassortment, indicating a new CCHFV circulating in Spain

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Summary

Introduction

In August 2018, a fatal autochthonous case of Crimean-Congo hemorrhagic fever was confirmed in western Spain. On August 7, infection with CCHF virus (CCHFV) was considered. On August 8, a blood sample was collected into an EDTA tube and sent to the National Center for Microbiology (Madrid, Spain) for CCHFV diagnostic testing.

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Conclusion
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