Abstract

Failure of Preventive Treatments in Migraine: An Observational Retrospective Study in a Tertiary Headache Center

Highlights

  • Despite the criteria of acute migraine treatment and prevention have been well described, there are still unmet needs, for a general underuse and low benefit of preventive treatments.The aim of the present study was to observe retrospectively the short term effect of preventive treatment in a cohort of migraine patients come at a tertiary headache center, using data from an electronic medical record

  • The rate of improvement was estimated on the triptans use reduction, and was even significantly lower among subjects treated with oral preventive therapies in comparison with those without these drugs, though a mild improvement was present in the group with chronic migraine [3]

  • General considerations on headache populations These real life data showed that in our south Italy tertiary headache center, the most of patients suffered from medium-high frequency migraine, not previously treated with preventive drugs, and only a minority of them used triptans

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Summary

Introduction

Despite the criteria of acute migraine treatment and prevention have been well described , there are still unmet needs, for a general underuse and low benefit of preventive treatments.The aim of the present study was to observe retrospectively the short term effect of preventive treatment in a cohort of migraine patients come at a tertiary headache center, using data from an electronic medical record. Despite the criteria of acute migraine treatment and prevention have been well described , there are still unmet needs, for a general underuse and low benefit of preventive treatments. Despite the criteria of acute episodes treatment and prevention have been well described [2], there are still a large proportion of patients with unmet needs, for a general underuse and low benefit of preventive treatments [3]. The French SMILE study, assessed the determinants of prescription of migraine preventive therapy among GPs and neurologists and factors determining eligibility, as frequency and severity of headache and scarce efficacy of acute treatment [5]. The study just underlined that the current use of preventive therapies is scarce and with negligible benefits, and that the most of migraine patients have currently unmet needs

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