Abstract
The mobility of many patients often depends on their using a motor vehicle. For this reason studies on their driving ability while under the influence of psychoactive drugs is of great practical relevance. These studies have shown that underlying factors of the illness itself represent a greater problem than drug-induced factors. When assessing pharmacologic effects on neuropsychological functions it has to be taken into account that patients' abilities take some time to stabilize after the acute phase of the disease. Driving ability while under the influence of psychoactive drugs must thus be judged over time. Marked interindividual variations in the reaction to psychoactive drugs always requires individual assessment of driving ability.
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