Abstract
Discussion and summarySome of the factors that are known to affect the agglutination of various erythrocytes by viruses are the age of the donor animal, the hydrogen ion concentration of the diluent and the temperatures at which erythrocytes are allowed to sediment. The results reported here indicate that these factors, either singly or in combination, also affect the agglutination of human erythrocytes by enteroviruses known to possess this property.Cord erythrocytes or diluents of specific hydrogen ion concentration are not usually necessary for demonstration of enterovirus hemagglutinins. However, the use of these cells and of diluents other than those buffered at or above pH 7.0 has enabled us to detect hemagglutinating activity where it existed in what might be termed a “borderline state.” This was exemplified by our demonstration of hemagglutination by ECHO virus type 24. Other reports(15,29,30) have indicated that the pH optimum for hemagglutination reactions with certain enteroviruses was other th...
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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