Abstract
Accuracy and precision in four clinical chemistry determinations (glucose, urea, total cholesterol, total proteins) have been investigated in a survey of 404 Italian laboratories. Inaccuracy and imprecision were found which appear, under the survey conditions, to be little related to factors such as class and size of laboratory, qualifications and seniority of analyst, and method of analysis. This would imply that acting upon these factors is less important in improving laboratory performance than is the systematic use of quality control methods.
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