Abstract
In the anticancer activity studies, Cu(II) complexes have been considered as the best alternative to cis-platin due to their biocompatibility and significant functions in biological systems. Synthesis of nanoparticles from the Schiff base transition metal complexes was one of the most suitable methods, because the products obtained were of good purity and with perfect structure. Based on this, herein, we have reported the synthesis of two CuO Nps from two Copper Schiff base complexes by the thermal decomposition method. The Schiff base complexes were characterized by FTIR, UV-vis, 1H NMR, PXRD, EPR spectra, and TGA studies. The CuO Nps synthesized were characterized by FTIR, XRD, SEM, and EDX analyses. All the studies confirm the formation of the CuO nanoparticles. The Cu(II) complexes as well as the CuO Nps were analyzed for the antibacterial and anticancer studies. Studies indicate the high biological activity of the Cu(II) complexes than the CuO Nps. The decrease in activity of the CuO Nps may be due to the diminishing size of the particles in complexes.
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