Abstract

Background: In these study we report here one-pot multi-component and solvent free Mannich reaction of U.V. absorbing material, five member heterocyclic ring system and amides/carbamates has been efficiently catalyzed by recyclable ethyl ammonium nitrate as ionic liquid at ambient temperature to produce mannich compounds in high yields. This method has advantages of mild condition, no environmental pollution, and simple work-up procedures to produce new mannich products 4(a-f). The synthesis of five member based heterocycles has been the point of attraction towards their pronounced biological activities and molecular docking studies. Keywords: Multi-component synthesis, heterocyclic compounds, UV absorbing materials, mannich products, molecular docking study.

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