Abstract
A green bioprocess for the fabrication of nanofiber membranes from the biomaterial polyamide 56 (PA56) via electrospinning was proposed. Cadaverine, as the precursor of PA56, was first produced from recombinant Escherichia coli using the whole-cell biotransformation of lysine. PA56 was then fabricated by mixing adipic acid with purified cadaverine obtained from solvent extraction and distillation. The thermal properties of the fabricated PA56 are as follows: a melting point of 250 °C, a crystallization point of 220 °C, and a degradation temperature of 410 °C. A PA56 nanofiber membrane (PAM) was further prepared via electrospinning. Dyed membranes (P-Dye) were obtained by the reaction of Reactive Red 141 dye with the amino group of PAM. Poly-(hexamethylene biguanide) (PHMB) was attached to the P-Dye to create P-Dye-PHMB. On the other hand, PAM with alginate, used to facilitate PHMB attachment (P-Alg-PHMB), was compared with P-Dye-PHMB in terms of antibacterial activity against pathogenic strains of E. coli and Pseudomonas putida. P-Alg-PHMB showed excellent antibacterial efficiency for E. coli (97%) and P. putida (100%). The proposed bioprocess can be used to fabricate novel membranes for biomedical applications and functional textiles.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
