Abstract

AbstractA nano‐porous polyoxazoline‐coated silicon tip was developed by ring opening polymerization of 2‐methyl‐2‐oxazoline. The tip surface modified with the nano‐porous polyoxazoline has pore sizes from 30 nm to 100 nm, which can easily absorb large‐molecular‐weight biomolecules in their pores. In combination with dip‐pen nanolithograpy (DPN) technique, this can generate protein nanostructures 60 times faster than what one can obtain with the conventional silicon tip. We discuss the fabrication of the nano‐porous polymers on the surface and how to use this novel tip for scanning probe lithography‐based nanopatterning of biomolecules.

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