Abstract
Mice with the hereditary obese hyperglycemic syndrome are unusually sensitive to the toxic action of caffeine. A single injection of caffeine, or the replacement of drinking water by coffee for 1 week causes a drastic and prolonged (2 or more months) elevation of blood glucose. Administration of purines and pyrimidines other than alloxan (shown previously to cause in this syndrome prolonged lowering of blood glucose and regranulation of beta cells) did not lead to striking results. No explanation for this unexpected effect of caffeine is offered.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
