Abstract

A young man presented with pneumocystis jiroveci pneumonia usually seen in immunocompromized individuals, and congestive heart failure due to dilated cardiomyopathy. He had been previously healthy but he self-treated his distant attacks of gouty arthritis with 40 mg prednisone/day over 7 years. Cushingoid appearance, abdominal striae, oral thrush, proximal myopathy, bilateral cataract, hyperglycaemia, hypertension, and osteoporosis were found. Premature atherosclerotic plaques were identified but none was obstructive or severe enough to account for the cardiomyopathy, which in the absence of an alternative explanation, we believe was also due the prolonged glucocorticoid administration, an unusual adverse event and an almost unprecedented cluster in a patient who had no indication to receive the drug.

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