Abstract
Extraskeletal myxoid chondrosarcoma (EMC) is a relatively rare but well-defined neoplasm. This report describes two patients, one with EMC of the buttock and one with EMC of the knee. The two cases presented with large lobed masses and long T1 and T2 signaling identified by magnetic resonance imaging (MRI). An enhanced MRI scan demonstrated enhancement of the tumors. The tumors were composed of strands or cords of oval and spindle cells embedded in abundant myxoid stroma. Pathology results confirmed EMC.
Highlights
Extraskeletal chondrosarcomas were first described by Stout and Verner in 1953 [1]; it was not until 1972 that extraskeletal myxoid chondrosarcoma (EMC) was histopathologically defined as its own entity [2]
Patients commonly present with non‐specific symptoms, including tenderness and the detection of a palpable mass [3]
The most common manifestation of EMC is an enlarging soft tissue mass; some lesions are accompanied by pain and tenderness, or may restrict the range of motion
Summary
Extraskeletal chondrosarcomas were first described by Stout and Verner in 1953 [1]; it was not until 1972 that extraskeletal myxoid chondrosarcoma (EMC) was histopathologically defined as its own entity [2]. This report presents two patients, one with EMC of the buttock and the other with EMC of the knee. Physical examination demonstrated that the right lower extremities and knee were slightly swollen with a palpable mass, but the patient had no difficulty in mobilization. Computed tomography (CT) revealed an irregular‐shaped soft tissue mass measuring 8.0x6.6x3.3 cm in size located in the right knee bursa, and the mass showed clear boundary and uniform density (Fig. 2A). MRI confirmed the presence of an irregular‐shaped soft tissue mass in right knee bursa with long T1 and T2 signaling, as well as a uniformed low signal in T1WI (Fig. 2B) and a high signal with fat suppression in T2WI (Fig. 2C). CKpan, and positive for S‐100 and vimentin Based on these findings, the patient was diagnosed with EMC
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