Abstract
The phenomenon of longevity and healthy aging as well as the factors that can slow down or even prevent the appearance of pathological conditions related to aging is a subject of interest in modern biology and medical research. In this context, a series of clinical and biochemical indicators are recorded and evaluated, as well as a wide variety of cellular aging biomarkers that include molecular signals and biomolecules at the proteomic, metabolomic, genomic and epigenetic level. The use of biomarkers to assess biological aging can help predict life expectancy and quality of life. The reliability of various biomarkers of aging should also be tested for validity against clinical markers of aging, such as frailty, loss of (physical) function, chronic diseases and disabilities.
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