Abstract
Ionising radiation can be produce different forms of DNA damage on living cells. Changes in biomarkers due to exposure to ionising radiation can be an appropriate tool for the immediate recognition of individuals exposed to radiation after a radiological accident or nuclear disaster. QPCR technique, as an approved method, can be used for analysing the expression levels of sensitive genes following radiation exposure. Gene expression studies were performed on a group of 36 radiation workers and 36 matched–normal people without a history of radiation exposure. Mean gene expression values for control and irradiated groups were compared. Mean gene expression values for control and irradiated groups were compared. There were significant differences between the mean gene expressions of Bax and Bcl–2 (p<0.05), in normal and irradiated groups. The logistic regression model is able to correctly identify 77.8% of irradiated samples (specificity) and 75.0% of normal samples (sensitivity).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
