Abstract
Alzheimers disease (AD) is a severe well-known cognitive disease, and it is also the most worldwide cause of dementia. Studies have shown that AD may have some interactions with the coronavirus disease 2019 (COVID-19) in some particular areas. This paper aims to figure out the potential associations how one causes the interplay of another, whether directly or indirectly. In addition, the paper provides a comprehensive mechanism underlying cognitive impairment also known as brain fog of COVID-19, including the effects on neurons and glial cells by persistent elevation of the chemokine CCL11. Then the paper provides drug-drug interaction with metabolized by same cytochrome enzymes lead to major changes in the pharmacology of treatments. Finally, the paper concludes the points mentioned about the associations between COVID-19 and AD then suggests the direction of the future studies.
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