Abstract
Book detailsEpigenetics: Linking Genotype and Phenotype in Developmentand Evolution, Hallgrimsson, B and Hall BK (Editors).University of California Press, Berkeley, Los Angeles,London. Viii + 459 pages, ISBN: 978-0-520-26709-I,Price: $85.45.Much of the theoretical and empirical basis of themodern evolutionary synthesis, and progress in appliedgenetics (e.g., plant and animal breeding), has beenbuilt on the premise that gene frequency changes inpopulations, in time (across generations) and space,occur due to the action of evolutionary forces. Empir-ical estimates of gene frequencies serve as indices toquantify micro-evolutionary changes. During the firsttwo decades of this phase in the 20
Highlights
Book details Epigenetics: Linking Genotype and Phenotype in Development and Evolution, Hallgrimsson, B and Hall BK (Editors)
While Wright and his contemporaries were developing mathematical theories to explain evolutionary processes and continued to do so, embryologist Conrad Hal Waddington started to explore these questions more formally starting with his famous paper “The Epigenetics”
According to the Wright-Waddington model, the space between genotype and phenotype (G-P space; Lewontin 1974), where epigenetic processes take place, may be viewed as the embedded system which orchestrates much of the antecedent and attendant properties of the G-P space
Summary
Book details Epigenetics: Linking Genotype and Phenotype in Development and Evolution, Hallgrimsson, B and Hall BK (Editors). A graphical representation of these ideas is provided in figure 1 of Wright's above paper with the legend: “...relation of factors (genes) to any developmental process of a vertebrate, occurring at a particular time and place”.
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