Abstract
Heinz bodies in erythrocytes of newborn or splenectomized humans exhibit a strongly positive alpha naphthyl acetate esterase reaction. In contrast, Heinz bodies formed by in vitro treatment of erythrocytes with phenylhydrazine show no enzyme activity. In rabbits acetylphenylhydrazine treatment also results in the production of enzyme-negative Heinz bodies in circulating erythrocytes, whereas bone marrow erythroblasts yield Heinz bodies of a distinctly enzyme-positive type. Erythrocytes with strongly enzyme-positive Heinz bodies are detectable in the blood of acetylphenylhydrazine-injected animals a few days later. This indicates that formation of enzyme-positive Heinz bodies results from an effect on the bone marrow.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
