Abstract

Researches on pulp regeneration based on odontogenic stem cells have made a breakthrough and some results have been applied clinically in recent years. It is demonstrated that exosomes secreted by stem cells play a significant role in tissue regeneration. Compared with stem cells, exosomes exhibit more advantages such as wider sources, more immediate effects, and less immune rejections, which are expected to be exploited in the pulp regeneration by cell-homing. In this review, the conventional dental pulp tissue engineering and exosomes-based dental pulp regeneration method are discussed, the new strategy for dental pulp regeneration by using exosomes is analyzed and proposed.

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